Icariside E4

Modify Date: 2024-01-17 17:38:40

Icariside E4 structure	Common Name	Icariside E4
	CAS Number	126253-42-7	Molecular Weight	506.54
	Density	1.348±0.06 g/cm3	Boiling Point	693.3±55.0 °C at 760 mmHg
	Molecular Formula	C₂₆H₃₄O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Icariside E4

Icariside E4 is an antinociceptive agent, and can be isolated from Tabebuia roseo-alba. Icariside E4 has peripheral analgesic activity by ATP-sensitive K+ channel-dependent mechanisms. Icariside E4 also has anti-oxidant, anti-Alzheimer and anti-inflammatory effects[1][2].

Name	Icariside E4

Description	Icariside E4 is an antinociceptive agent, and can be isolated from Tabebuia roseo-alba. Icariside E4 has peripheral analgesic activity by ATP-sensitive K+ channel-dependent mechanisms. Icariside E4 also has anti-oxidant, anti-Alzheimer and anti-inflammatory effects[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Veiga TA, et al. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43. [2]. Suh JY, et al. Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells. Phytother Res. 2023 Jan;37(1):7-14.

Description

Related Catalog

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

References

[1]. Veiga TA, et al. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43.

[2]. Suh JY, et al. Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells. Phytother Res. 2023 Jan;37(1):7-14.