m-PEG2-O-Ph-3-NH2

Modify Date: 2024-01-05 18:14:55

m-PEG2-O-Ph-3-NH2 Structure
m-PEG2-O-Ph-3-NH2 structure
 Common Name m-PEG2-O-Ph-3-NH2
CAS Number 126415-02-9 Molecular Weight 211.258
Density 1.1±0.1 g/cm3 Boiling Point 346.2±27.0 °C at 760 mmHg
Molecular Formula C11H17NO3 Melting Point N/A
MSDS N/A Flash Point 173.9±17.4 °C

 Use of m-PEG2-O-Ph-3-NH2


m-PEG2-O-Ph-3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-[2-(2-Methoxyethoxy)ethoxy]aniline
Synonym More Synonyms

 m-PEG2-O-Ph-3-NH2 Biological Activity

Description m-PEG2-O-Ph-3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 346.2±27.0 °C at 760 mmHg
Molecular Formula C11H17NO3
Molecular Weight 211.258
Flash Point 173.9±17.4 °C
Exact Mass 211.120850
LogP 0.14
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.521

 Synonyms

Benzenamine, 3-[2-(2-methoxyethoxy)ethoxy]-
MFCD11652541
3-[2-(2-Methoxyethoxy)ethoxy]aniline
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Chemsrc provides m-PEG2-O-Ph-3-NH2(CAS#:126415-02-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of m-PEG2-O-Ph-3-NH2 are included as well.>> amp version: m-PEG2-O-Ph-3-NH2

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