Sarafotoxin A

Modify Date: 2024-01-02 13:59:26

Sarafotoxin A structure	Common Name	Sarafotoxin A
	CAS Number	126738-34-9	Molecular Weight	2514.85000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀₅H₁₅₆N₂₈O₃₄S₅	Melting Point	N/A
	MSDS	Chinese	Flash Point	N/A

Use of Sarafotoxin A

Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM[1].

Name	Sarafotoxin S6a
Synonym	More Synonyms

Description	Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor Research Areas >> Neurological Disease
Target	ETB ETA
In Vitro	Sarafotoxin S6a is a rather weak agonist effect in guinea-pig aorta, the eliting concentration (EC50) is 150 nM in guinea-pig aorta[1].
References	[1]. P Schoeffter, et al. Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur J Pharmacol