NHI 2

Modify Date: 2024-01-20 12:42:52

NHI 2 Structure
NHI 2 structure
Common Name NHI 2
CAS Number 1269802-97-2 Molecular Weight 335.277
Density 1.4±0.1 g/cm3 Boiling Point 495.7±55.0 °C at 760 mmHg
Molecular Formula C17H12F3NO3 Melting Point N/A
MSDS USA Flash Point 253.6±31.5 °C

 Use of NHI 2


NHI-2 is a potent inhibitor of LDH-A. NHI-2 is an efficient anti-glycolytic agent. NHI-2 has the potential for the research of cancer disease[1].

 Names

Name Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate
Synonym More Synonyms

 NHI 2 Biological Activity

Description NHI-2 is a potent inhibitor of LDH-A. NHI-2 is an efficient anti-glycolytic agent. NHI-2 has the potential for the research of cancer disease[1].
Related Catalog
References

[1]. Granchi C, et al. Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds. Org Biomol Chem. 2013;11(38):6588-6596.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 495.7±55.0 °C at 760 mmHg
Molecular Formula C17H12F3NO3
Molecular Weight 335.277
Flash Point 253.6±31.5 °C
Exact Mass 335.076935
LogP 5.14
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.567

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate
1H-Indole-2-carboxylic acid, 1-hydroxy-6-phenyl-4-(trifluoromethyl)-, methyl ester