H-Abu-OH-d6

Modify Date: 2024-01-13 17:30:43

H-Abu-OH-d6 structure	Common Name	H-Abu-OH-d6
	CAS Number	1276197-51-3	Molecular Weight	109.16
	Density	1.1±0.1 g/cm3	Boiling Point	215.2±23.0 °C at 760 mmHg
	Molecular Formula	C₄H₃D₆NO₂	Melting Point	>245°C
	MSDS	N/A	Flash Point	83.9±22.6 °C

Use of H-Abu-OH-d6

H-Abu-OH-d6 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

Name	L-2-Aminobutyric Acid-d6
Synonym	More Synonyms

Description	H-Abu-OH-d6 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Yudkoff M, et al. On the clinical significance of the plasma alpha-amino-n-butyric acid:leucine ratio. Am J Clin Nutr. 1979 Feb;32(2):282-5.

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Yudkoff M, et al. On the clinical significance of the plasma alpha-amino-n-butyric acid:leucine ratio. Am J Clin Nutr. 1979 Feb;32(2):282-5.

Density	1.1±0.1 g/cm3
Boiling Point	215.2±23.0 °C at 760 mmHg
Melting Point	>245°C
Molecular Formula	C₄H₃D₆NO₂
Molecular Weight	109.16
Flash Point	83.9±22.6 °C
Exact Mass	109.100990
LogP	-0.15
Vapour Pressure	0.1±0.9 mmHg at 25°C
Index of Refraction	1.462
Storage condition	-20C

(2S)-2-Amino(2H6)butanoic acid

Butanoic-2,3,3,4,4,4-d6 acid, 2-amino-, (2S)-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: H-Abu-OH-d6
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Purity: 98.0%
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H-Abu-OH-d6

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