N-acetyl lysyltyrosylcysteine amide
Modify Date: 2024-01-15 20:29:59
N-acetyl lysyltyrosylcysteine amide structure
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Common Name | N-acetyl lysyltyrosylcysteine amide | ||
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| CAS Number | 1287585-40-3 | Molecular Weight | 453.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H31N5O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of N-acetyl lysyltyrosylcysteine amideN-acetyl lysyltyrosylcysteine amide (KYC) is a potent, tripeptide inhibitor of myeloperoxidase (MPO), inhibits MPO-mediated hypochlorous acid (HOCl) formation (IC50=7 uM) and nitration/oxidation of LDL; completely inhibits HOCl production at 25 uM, decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice; reduces oxidative stress-mediated inflammation, neuronal damage, and neural stem cell injury in murine model of stroke. |
| Name | N-acetyl lysyltyrosylcysteine amide |
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| Description | N-acetyl lysyltyrosylcysteine amide (KYC) is a potent, tripeptide inhibitor of myeloperoxidase (MPO), inhibits MPO-mediated hypochlorous acid (HOCl) formation (IC50=7 uM) and nitration/oxidation of LDL; completely inhibits HOCl production at 25 uM, decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice; reduces oxidative stress-mediated inflammation, neuronal damage, and neural stem cell injury in murine model of stroke. |
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| References | References 1. Zhang H, et al. J Lipid Res. 2013 Nov;54(11):3016-29. 2. Zhang H, et al. J Lipid Res. 2013 Nov;54(11):3009-15. 3. Yu G, et al. J Neuroinflammation. 2016 May 24;13(1):119. 4. Rymaszewski AL, et al. Cancers (Basel). 2014 May 9;6(2):1111-27. View Related Products by Target Other Targets |
| Molecular Formula | C20H31N5O5S |
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| Molecular Weight | 453.56 |
| Hazard Codes | Xi |
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- DC Chemicals Limited
- China
- Product Name: N-acetyl lysyltyrosylcysteine amide
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: N-acetyl lysyltyrosylcysteine amide
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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