L 669262

Modify Date: 2024-01-06 18:45:40

L 669262 Structure
L 669262 structure
Common Name L 669262
CAS Number 130468-11-0 Molecular Weight 432.55
Density 1.16g/cm3 Boiling Point 609.5ºC at 760mmHg
Molecular Formula C25H36O6 Melting Point N/A
MSDS N/A Flash Point 202.1ºC

 Use of L 669262


L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC50 of 0.10 ng/mL for rat liver HMG-CoA[1].

 Names

Name [(1S,7S,8S,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-6-oxo-2,7,8,8a-tetrahydro-1H-naphthalen-1-yl] 2,2-dimethylbutanoate
Synonym More Synonyms

 L 669262 Biological Activity

Description L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC50 of 0.10 ng/mL for rat liver HMG-CoA[1].
Related Catalog
References

[1]. Joshua H, et, al. L-669,262, a potent HMG-CoA reductase inhibitor. J Antibiot (Tokyo). 1991 Mar;44(3):366-70.  

 Chemical & Physical Properties

Density 1.16g/cm3
Boiling Point 609.5ºC at 760mmHg
Molecular Formula C25H36O6
Molecular Weight 432.55
Flash Point 202.1ºC
Exact Mass 432.25100
PSA 89.90000
LogP 3.90870
Vapour Pressure 2.11E-17mmHg at 25°C
Index of Refraction 1.536

 Synonyms

l-669,262