Ethionine

Modify Date: 2024-01-02 17:41:33

Ethionine Structure
Ethionine structure
Common Name Ethionine
CAS Number 13073-35-3 Molecular Weight 163.24
Density 1.2±0.1 g/cm3 Boiling Point 310.4±37.0 °C at 760 mmHg
Molecular Formula C6H13NO2S Melting Point 280ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 141.5±26.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Ethionine


L-Ethionine (L-ETH) is aamino acids and their derivatives.

 Names

Name L-ethionine
Synonym More Synonyms

 Ethionine Biological Activity

Description L-Ethionine (L-ETH) is aamino acids and their derivatives.
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 310.4±37.0 °C at 760 mmHg
Melting Point 280ºC (dec.)(lit.)
Molecular Formula C6H13NO2S
Molecular Weight 163.24
Flash Point 141.5±26.5 °C
Exact Mass 163.066696
PSA 88.62000
LogP 0.90
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.524

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ES6825300
CHEMICAL NAME :
Butyric acid, 2-amino-4-(ethylthio)-, L-
CAS REGISTRY NUMBER :
13073-35-3
BEILSTEIN REFERENCE NO. :
1722528
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C6-H13-N-O2-S
MOLECULAR WEIGHT :
163.26
WISWESSER LINE NOTATION :
QVYZ2S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
44100 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
5 mmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1059,1987

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS ES6825300
HS Code 2930909090

 Synthetic Route

~62%

Ethionine Structure

Ethionine

CAS#:13073-35-3

Literature: Singh, Shanteri; Zhang, Jianjun; Huber, Tyler D.; Sunkara, Manjula; Hurley, Katherine; Goff, Randal D.; Wang, Guojun; Zhang, Wen; Liu, Chunming; Rohr, Juergen; Van Lanen, Steven G.; Morris, Andrew J.; Thorson, Jon S. Angewandte Chemie - International Edition, 2014 , vol. 53, # 15 p. 3965 - 3969 Angew. Chem., 2014 , vol. 53-126, # 15 p. 4046 - 4050

~%

Ethionine Structure

Ethionine

CAS#:13073-35-3

Literature: Journal of the American Chemical Society, , vol. 73, p. 2497

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Ethionine Structure

Ethionine

CAS#:13073-35-3

Literature: Tetrahedron Asymmetry, , vol. 8, # 19 p. 3197 - 3200

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Ethionine Structure

Ethionine

CAS#:13073-35-3

Literature: Journal of Biological Chemistry, , vol. 179, p. 1050

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Ethionine Structure

Ethionine

CAS#:13073-35-3

Literature: Agricultural and Biological Chemistry, , vol. 48, # 8 p. 1991 - 1996

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Ethionine Structure

Ethionine

CAS#:13073-35-3

Literature: Monatshefte fur Chemie, , vol. 131, # 6 p. 667 - 672

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles41

More Articles
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...

The Japanese toxicogenomics project: application of toxicogenomics.

Mol. Nutr. Food. Res. 54 , 218-27, (2010)

Biotechnology advances have provided novel methods for the risk assessment of chemicals. The application of microarray technologies to toxicology, known as toxicogenomics, is becoming an accepted appr...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

 Synonyms

Homocysteine S-Ethyl Ether
(S)-2-amino-4-(ethylthio)butanoic acid
L-2-amino-4-(ethylthio)butanoic acid
S-Ethyl-L-homocysteine
L-Homocysteine, S-ethyl-
(+)-S-ethyl-L-homocysteine
MFCD00002626
L-Homocysteine,S-ethyl-
(+)-ethionine
Ethionine
EINECS 235-966-4
L-S-Ethylhomocysteine
(L)-Ethionine
a-Amino-g-(ethylmercapto)butyric Acid
(2S)-2-amino-4-(ethylsulfanyl)butanoic acid
L-Ethionine
L-Homocysteine, S-ethyl-.
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