a-FABP-IN-1

Modify Date: 2024-04-05 19:27:08

a-FABP-IN-1 Structure
a-FABP-IN-1 structure
Common Name a-FABP-IN-1
CAS Number 1310361-52-4 Molecular Weight 515.02
Density 1.3±0.1 g/cm3 Boiling Point 654.3±55.0 °C at 760 mmHg
Molecular Formula C29H23ClN2O3S Melting Point N/A
MSDS N/A Flash Point 349.5±31.5 °C

 Use of a-FABP-IN-1


a-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a Ki below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production[1].

 Names

Name HM 50316
Synonym More Synonyms

 a-FABP-IN-1 Biological Activity

Description a-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a Ki below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production[1].
Related Catalog
Target

Ki: <1.0 nM (a-FABP)[1]

References

[1]. Liu X, et al. New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg Med Chem Lett. 2011 May 15;21(10):2949-52.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 654.3±55.0 °C at 760 mmHg
Molecular Formula C29H23ClN2O3S
Molecular Weight 515.02
Flash Point 349.5±31.5 °C
Exact Mass 514.111816
LogP 8.09
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.651

 Synonyms

compound 5g [PMID: 21481589]
2-({2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl]-3-biphenylyl}oxy)-2-methylpropanoic acid
Propanoic acid, 2-[[2'-[1-(4-chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methyl-
2-[[2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methylpropanoic acid