Peptide P60

Modify Date: 2024-01-13 15:25:05

Peptide P60 Structure
Peptide P60 structure
Common Name Peptide P60
CAS Number 1319725-20-6 Molecular Weight 1994.369
Density N/A Boiling Point N/A
Molecular Formula C95H132N24O20S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Peptide P60


Peptide P60 (FOXP3 inhibitor P60) is a 15-mer synthetic peptide, cell-permeable inhibitor of FOXP3, binds specifically to FOXP3; inhibits murine and human-derived Treg and improves effector T cell stimulation, overcomes the inhibitory effect of FOXP3 on the activity of the transcription factors NF-κB and NFAT, inhibits upregulation of mRNA for Foxp3 and IL-10 on effector T cells and enhances mRNA for IFN-γ after anti-CD3 stimulation; induces a scurfy-like disease in newborn mice, improves vaccine efficacy in mice model of CT26 tumor and HCV infection.

 Names

Name Peptide P60

 Peptide P60 Biological Activity

Description Peptide P60 (FOXP3 inhibitor P60) is a 15-mer synthetic peptide, cell-permeable inhibitor of FOXP3, binds specifically to FOXP3; inhibits murine and human-derived Treg and improves effector T cell stimulation, overcomes the inhibitory effect of FOXP3 on the activity of the transcription factors NF-κB and NFAT, inhibits upregulation of mRNA for Foxp3 and IL-10 on effector T cells and enhances mRNA for IFN-γ after anti-CD3 stimulation; induces a scurfy-like disease in newborn mice, improves vaccine efficacy in mice model of CT26 tumor and HCV infection.
References References 1. Casares N, et al. J Immunol. 2010 Nov 1;185(9):5150-9. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C95H132N24O20S2
Molecular Weight 1994.369