Thymidine-d2
Modify Date: 2024-01-04 06:30:38
Thymidine-d2 structure
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Common Name | Thymidine-d2 | ||
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| CAS Number | 132376-92-2 | Molecular Weight | 244.24100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H12D2N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thymidine-d2Thymidine-d2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1 |
| Name | [5',5''-2h2]thymidine |
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| Synonym | More Synonyms |
| Description | Thymidine-d2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1 |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C10H12D2N2O5 |
|---|---|
| Molecular Weight | 244.24100 |
| Exact Mass | 244.10300 |
| PSA | 104.55000 |
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~71%
Thymidine-d2 CAS#:132376-92-2 |
| Literature: Frank; Worth Jr.; Christner; Kozarich; Stubbe; Kappen; Goldberg Journal of the American Chemical Society, 1991 , vol. 113, # 6 p. 2271 - 2275 |
| Precursor 1 | |
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| DownStream 0 | |
| diethyl 3,3'-diethyl-4,4'-dimethyl-2,2'-dipyrrylmethane-5,5'-dicarboxylate |
| diethyl 3,3'-diethyl-4,4'-dimethyl-2,2'-dipyrromethane-5,5'-dicaboxylate |