Dihydrocapsaicin-d3

Modify Date: 2024-01-13 10:05:05

Dihydrocapsaicin-d3 Structure
Dihydrocapsaicin-d3 structure
Common Name Dihydrocapsaicin-d3
CAS Number 1330261-21-6 Molecular Weight 310.45
Density N/A Boiling Point N/A
Molecular Formula C18H26D3NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dihydrocapsaicin-d3


Dihydrocapsaicin-d3is the deuterium labeledDihydrocapsaicin(HY-N0361)[1]. Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[2][3][4].

 Names

Name Dihydro Capsaicin-d3

 Dihydrocapsaicin-d3 Biological Activity

Description Dihydrocapsaicin-d3is the deuterium labeledDihydrocapsaicin(HY-N0361)[1]. Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[2][3][4].
Related Catalog
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C18H26D3NO3
Molecular Weight 310.45