α2β1 Integrin Recognition Sequence

Modify Date: 2024-01-03 18:07:55

α2β1 Integrin Recognition Sequence structure	Common Name	α2β1 Integrin Recognition Sequence
	CAS Number	134580-64-6	Molecular Weight	390.34600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₂₂N₄O₉	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of α2β1 Integrin Recognition Sequence

α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1].

Name	(4S)-4-[[2-[[(2S)-2-amino-3-carboxypropanoyl]amino]acetyl]amino]-5-[[(1S)-1-carboxyethyl]amino]-5-oxopentanoic acid
Synonym	More Synonyms

Description	α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cytoskeleton >> Integrin
References	[1]. Graham KL, et al. Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences. J Virol. 2004 Nov;78(21):11786-97.

Molecular Formula	C₁₄H₂₂N₄O₉
Molecular Weight	390.34600
Exact Mass	390.13900
PSA	235.69000
LogP	0.06470

α2β1 Integrin Recognition Sequence MSDS(Chinese)

RIDADR	NONH for all modes of transport

Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.

J. Biol. Chem. 266 , 7363-7367, (1991)

The alpha 2 beta 1 integrin serves as either a specific cell surface receptor for collagen or as both a collagen and laminin receptor depending upon the cell type. Recently we established that the alp...

RGDS and DGEA-induced [Ca2+]i signalling in human dermal fibroblasts.

Biochim. Biophys. Acta Mol. Cell Res. 1746(1) , 28-37, (2005)

A pulse of short peptides, RGDS and DGEA in the millimolar range, immediately elicits in normal human fibroblasts a transient increase of intracellular Ca2+ ([Ca2+]i). In the present study, we show th...

Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.

PLoS ONE 8 , e59558, (2013)

Glioma initiating cells (GICs) are considered responsible for the therapeutic resistance and recurrence of malignant glioma. To clarify the molecular mechanism of GIC maintenance/differentiation, we e...

L-|A-Aspartylglycyl-L-|A-glutamyl-L-alanine

|A2|A1 Integrin Recognition Sequence

H-Asp-Gly-Glu-Ala-OH

DGEA