hydroflumethiazide
hydroflumethiazide structure
|
Common Name | hydroflumethiazide | ||
|---|---|---|---|---|
| CAS Number | 135-09-1 | Molecular Weight | 331.29200 | |
| Density | 1.678g/cm3 | Boiling Point | 531.6ºC at 760 mmHg | |
| Molecular Formula | C8H8F3N3O4S2 | Melting Point | 272-273ºC | |
| MSDS | Chinese USA | Flash Point | 275.3ºC | |
| Symbol |
GHS08 |
Signal Word | Danger | |
Use of hydroflumethiazideHydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas[1][2][3]. |
| Name | 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide |
|---|---|
| Synonym | More Synonyms |
| Description | Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas[1][2][3]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.678g/cm3 |
|---|---|
| Boiling Point | 531.6ºC at 760 mmHg |
| Melting Point | 272-273ºC |
| Molecular Formula | C8H8F3N3O4S2 |
| Molecular Weight | 331.29200 |
| Flash Point | 275.3ºC |
| Exact Mass | 330.99100 |
| PSA | 135.12000 |
| LogP | 3.34280 |
| Vapour Pressure | 2.2E-11mmHg at 25°C |
| Index of Refraction | 1.55 |
| Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H317-H334 |
| Precautionary Statements | P261-P280-P284-P304 + P340-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn,Xi |
| Risk Phrases | R42/43 |
| Safety Phrases | S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | DK9625000 |
| HS Code | 2935009090 |
|
~%
hydroflumethiazide CAS#:135-09-1 |
| Literature: Journal of the American Chemical Society, , vol. 81, p. 4807,4808 |
|
~%
hydroflumethiazide CAS#:135-09-1 |
| Literature: Journal of the American Chemical Society, , vol. 82, p. 1132 - 1135 |
|
~%
hydroflumethiazide CAS#:135-09-1 |
| Literature: Journal of the American Chemical Society, , vol. 81, p. 4807,4808 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Do thiazides reduce intestinal oxalate absorption?: a study in vitro using rabbit colon.
Clin. Sci. 86(3) , 353-7, (1994) 1. The purpose of the present study was to examine the effects of various diuretics on intestinal oxalate transport. Transmural oxalate fluxes were measured across isolated, short-circuited tissue seg... |
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Comparative effects of LN 5330 and diazoxide on insulin release and 86Rb+ permeability in perifused rat islets of Langerhans.
Biochem. Pharmacol. 42(4) , 787-91, (1991) The benzothiadiazine derivative LN 5330 (chloro-7 trifluoromethyl-6 benzothiadiazine-1,2,4-dioxide-1,1) has been shown to inhibit insulin secretion and calcium uptake. The present study was carried ou... |
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Metabolic effects of propranolol and hydroflumethiazide treatment in Kenyans with mild to moderate essential hypertension.
East Afr. Med. J. 70(11) , 696-700, (1993) In a prospective single-blind comparative trial, sixty newly diagnosed mild to moderate hypertensives were randomly assigned to either propranolol or hydroflumethiazide monotherapy. Baseline fasting s... |
| EINECS 205-173-8 |
| Robezon |
| Spandiuril |
| Saluron |
| MFCD00057316 |
| hydroflumethyazide |
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| hydroflumenthiazide |
| Diurometon |
| hydroflumethiazide |
| Flutizide |
| Hidroflumetiazid |
| Diuredemina |
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