Triclabendazole-D3

Modify Date: 2024-01-06 09:00:26

Triclabendazole-D3 Structure
Triclabendazole-D3 structure
Common Name Triclabendazole-D3
CAS Number 1353867-93-2 Molecular Weight 362.68
Density 1.6±0.1 g/cm3 Boiling Point 495.9±55.0 °C at 760 mmHg
Molecular Formula C14H6D3Cl3N2OS Melting Point N/A
MSDS USA Flash Point 253.7±31.5 °C

 Use of Triclabendazole-D3


Triclabendazole-d3 is the deuterium labeled 4-Methoxybenzylamine[1].

 Names

Name Triclabendazole-D3
Synonym More Synonyms

 Triclabendazole-D3 Biological Activity

Description Triclabendazole-d3 is the deuterium labeled 4-Methoxybenzylamine[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 495.9±55.0 °C at 760 mmHg
Molecular Formula C14H6D3Cl3N2OS
Molecular Weight 362.68
Flash Point 253.7±31.5 °C
Exact Mass 360.968933
LogP 5.97
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.724

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

MFCD20264917
Triclabendazole-(methyl-d3)
1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methyl-d3-thio)-
5-Chloro-6-(2,3-dichlorophenoxy)-2-[(2H3)methylsulfanyl]-1H-benzimidazole
5-Chloro-6-(2,3-dichlorophenoxy)-2-(methyl-d3-thio)-1H-benzimidazole