Indacaterol-d3

Modify Date: 2024-01-10 23:59:25

Indacaterol-d3 structure	Common Name	Indacaterol-d3
	CAS Number	2699828-16-3	Molecular Weight	395.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₅D₃N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Indacaterol-d3

Indacaterol-d3 is deuterium labeled Indacaterol.

Name	Indacaterol-d3

Description	Indacaterol-d3 is deuterium labeled Indacaterol.
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Battram, C., et al., In vitro and in vivo pharmacological characterization of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-o ne (indacaterol), a novel inhaled beta(2) adrenoceptor agonist with a 24-h duration of action. J Pharmacol Exp Ther, 2006. 317(2): p. 762-70. [3]. Sturton, R.G., et al., Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices. J Pharmacol Exp Ther, 2008. 324(1): p. 270-5.

Molecular Formula	C₂₄H₂₅D₃N₂O₃
Molecular Weight	395.51