Thiol-C10-amide-PEG8

Modify Date: 2024-01-16 15:48:17

Thiol-C10-amide-PEG8 Structure
Thiol-C10-amide-PEG8 structure
Common Name Thiol-C10-amide-PEG8
CAS Number 1353948-95-4 Molecular Weight 569.79
Density N/A Boiling Point N/A
Molecular Formula C27H55NO9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thiol-C10-amide-PEG8


Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thiol-C10-amide-PEG8

 Thiol-C10-amide-PEG8 Biological Activity

Description Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H55NO9S
Molecular Weight 569.79