Angiotensin III, human, mouse(Acetate)

Modify Date: 2024-01-02 11:42:09

Angiotensin III, human, mouse(Acetate) structure	Common Name	Angiotensin III, human, mouse(Acetate)
	CAS Number	13602-53-4	Molecular Weight	931.09100
	Density	1.39g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₆H₆₆N₁₂O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Angiotensin III, human, mouse(Acetate)

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.

Name	angiotensin iii, human
Synonym	More Synonyms

Description	Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Peptides Research Areas >> Cardiovascular Disease
Target	IC50: 0.648 nM (AT2R), 21.1 nM (AT1R)[1]
In Vitro	Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively[1].
In Vivo	Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats[3].
References	[1]. Bosnyak S, et al. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (Lond). 2011 Oct;121(7):297-303. [2]. Kemp BA, et al. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension. 2012 Aug;60(2):387-95. [3]. Gao J, et al. A new strategy for treating hypertension by blocking the activity of the brain renin-angiotensin system with aminopeptidase A inhibitors. Clin Sci (Lond). 2014 Aug;127(3):135-48.

Density	1.39g/cm3
Molecular Formula	C₄₆H₆₆N₁₂O₉
Molecular Weight	931.09100
Exact Mass	930.50800
PSA	339.94000
LogP	3.71910
Index of Refraction	1.657
Storage condition	−20°C
Water Solubility	H2O: 1.0 mg/mL, clear, colorless

WGK Germany	3

angiotensin I-converting enzyme

ACE INACTIVATOR

ANGIOTENSIN I-CONVERTING ENZYME INACTIVATOR

human AngIII

angiotensin III

CYANOAC-PHE-PHE-OH

H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH

CYANOAC-PHE-PHE

Angiotensin III, human, mouse

Zhejiang Hangyu API Co., Ltd
China
Product Name: Angiotensin III
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

Get all suppliers and price by the below link:

Angiotensin III, human, mouse(Acetate) suppliers

Price: ￥600/5 mg

Reference only. check more Angiotensin III, human, mouse(Acetate) price