L-Phenylalanine-3-13C

Modify Date: 2024-01-02 12:23:02

L-Phenylalanine-3-13C Structure
L-Phenylalanine-3-13C structure
Common Name L-Phenylalanine-3-13C
CAS Number 136056-02-5 Molecular Weight 166.18200
Density N/A Boiling Point N/A
Molecular Formula C813CH11NO2 Melting Point 270-275ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

 Use of L-Phenylalanine-3-13C


L-Phenylalanine-3-13C ((S)-2-Amino-3-phenylpropionic acid-3-13C) is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

 Names

Name (2R)-2-amino-3-phenylpropanoic acid
Synonym More Synonyms

 L-Phenylalanine-3-13C Biological Activity

Description L-Phenylalanine-3-13C ((S)-2-Amino-3-phenylpropionic acid-3-13C) is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Melting Point 270-275ºC (dec.)(lit.)
Molecular Formula C813CH11NO2
Molecular Weight 166.18200
Exact Mass 166.08200
PSA 63.32000
LogP 1.34130

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

L-Phenylalanine-3-13C
MFCD00084040
L-Phenylalanine-|A-13C