DPP-IV-IN-2

Modify Date: 2026-07-16 14:31:11

DPP-IV-IN-2 Structure
DPP-IV-IN-2 structure
Common Name DPP-IV-IN-2
CAS Number 136259-18-2 Molecular Weight 378.42300
Density N/A Boiling Point N/A
Molecular Formula C18H26N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DPP-IV-IN-2


DPP-IV-IN-2 is an inhibitor of both dipeptidyl peptidase IV (DPIV) and DP8/9 with IC50s of 0.1 and 0.95 μM, respectively.

 Names

Name H-Lys(4-nitro-Z)-pyrrolidide
Synonym More Synonyms

 DPP-IV-IN-2 Biological Activity

Description DPP-IV-IN-2 is an inhibitor of both dipeptidyl peptidase IV (DPIV) and DP8/9 with IC50s of 0.1 and 0.95 μM, respectively.
Related Catalog
Target

IC50: 0.1 μM (DPIV), 0.95 μM (DP8/9)[1]

References

[1]. Ansorge S, et al. Novel aspects of cellular action of dipeptidyl peptidase IV/CD26. Biol Chem. 2011 Mar;392(3):153-68.

 Chemical & Physical Properties

Molecular Formula C18H26N4O5
Molecular Weight 378.42300
Exact Mass 378.19000
PSA 130.48000
LogP 3.49330
InChIKey YDYSCRZHYWLSPQ-INIZCTEOSA-N
SMILES NC(CCCCNC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)N1CCCC1

 DPP-IV-IN-2Bioassay

View more

Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4513082
Name: Inhibition of DPP9
Source: ChEMBL
Target: Dipeptidyl peptidase 9
External Id: CHEMBL988356
Name: Inhibition of DPP8
Source: ChEMBL
Target: Dipeptidyl peptidase 8
External Id: CHEMBL988355
Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
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 Synonyms

lys(4-nitro-Z)pyrrolidide
Lys-Z-nitro-pyrrolidine
Lys[Z(NO2)] pyrrolidide
DPP-IV-IN-2
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