GNI-50
Modify Date: 2024-04-03 12:59:08
GNI-50 structure
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Common Name | GNI-50 | ||
|---|---|---|---|---|
| CAS Number | 1363154-45-3 | Molecular Weight | 402.469 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H22N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GNI-50GNI-50 is a potent, selective Nampt inhibitor with enzyme IC50 of 7 nM, A2780 cellular IC50 of 32 nM.GNI-50 showed excellent in vivo antitumor efficacy when dosed orally in an A2780 ovarian tumor xenograft model (TGI of 97% was observed on day 17). |
| Name | GNI-50 |
|---|
| Description | GNI-50 is a potent, selective Nampt inhibitor with enzyme IC50 of 7 nM, A2780 cellular IC50 of 32 nM.GNI-50 showed excellent in vivo antitumor efficacy when dosed orally in an A2780 ovarian tumor xenograft model (TGI of 97% was observed on day 17). |
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| References | 1. Zheng X, et al. J Med Chem. 2013 Jun 27;56(12):4921-37. |
| Molecular Formula | C19H22N4O4S |
|---|---|
| Molecular Weight | 402.469 |