MSN-50
Modify Date: 2024-01-13 11:04:31
MSN-50 structure
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Common Name | MSN-50 | ||
|---|---|---|---|---|
| CAS Number | 1592908-75-2 | Molecular Weight | 688.61 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H38BrN3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MSN-50MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection[1][2]. |
| Name | MSN-50 |
|---|
| Description | MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection[1][2]. |
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| Related Catalog | |
| Target |
Bax Bak |
| In Vitro | MSN-50 (0~10 uM) inhibits dye release from liposomes in a concentration-dependent fashion. MSN-50 (0~40 uM) inhibits tBid/Bax-mediated MOMP (mitochondrial outer membrane permeabilization) in a concentration-dependent manner and shows concentration-dependent inhibition of Bak-mediated MOMP. MSN-50 inhibits both Bax and Bak after activation by either cBid or Bim. MSN-50 (5 μM; BMK cells) inhibits apoptosis induced by actinomycin D and staurosporin (STS)[1][2]. |
| References |
| Molecular Formula | C36H38BrN3O6 |
|---|---|
| Molecular Weight | 688.61 |
| Hazard Codes | Xi |
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