FK 888
Modify Date: 2024-01-12 12:23:56
FK 888 structure
|
Common Name | FK 888 | ||
|---|---|---|---|---|
| CAS Number | 138449-07-7 | Molecular Weight | 588.70 | |
| Density | 1.26g/cm3 | Boiling Point | 901.9ºC at 760mmHg | |
| Molecular Formula | C36H36N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 499.2ºC | |
Use of FK 888FK888 is a potent, selective, and high affinity dipeptide NK1 receptor antagonist. FK888 displaces [3H]-SP binding with a Ki value of 0.69 nM and 0.45 microM. FK888 also inhibits SP-induced airway oedema in guinea-pig after both intravenous and oral administration[1]. |
| Name | (2S,4R)-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-4-hydroxy-1-(1-methylindole-3-carbonyl)pyrrolidine-2-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | FK888 is a potent, selective, and high affinity dipeptide NK1 receptor antagonist. FK888 displaces [3H]-SP binding with a Ki value of 0.69 nM and 0.45 microM. FK888 also inhibits SP-induced airway oedema in guinea-pig after both intravenous and oral administration[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.26g/cm3 |
|---|---|
| Boiling Point | 901.9ºC at 760mmHg |
| Molecular Formula | C36H36N4O4 |
| Molecular Weight | 588.70 |
| Flash Point | 499.2ºC |
| Exact Mass | 588.27400 |
| PSA | 94.88000 |
| LogP | 4.62180 |
| Vapour Pressure | 5.08E-35mmHg at 25°C |
| Index of Refraction | 1.658 |
| hms3269a13 |
| fk 888 |