CT-721

Modify Date: 2024-01-12 10:16:20

CT-721 Structure
CT-721 structure
Common Name CT-721
CAS Number 1388710-60-8 Molecular Weight 525.04
Density N/A Boiling Point N/A
Molecular Formula C30H29ClN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CT-721


CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities[1].

 Names

Name CT-721

 CT-721 Biological Activity

Description CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities[1].
Related Catalog
Target

IC50: 21.3 nM (wild-type Bcr-Abl kinase)[1]

References

[1]. Sun Y, et al. CT-721, a Potent Bcr-Abl Inhibitor, Exhibits Excellent In Vitro and In Vivo Efficacy in the Treatment of Chronic Myeloid Leukemia. J Cancer. 2017 Aug 23;8(14):2774-2784.

 Chemical & Physical Properties

Molecular Formula C30H29ClN6O
Molecular Weight 525.04

 Safety Information

Hazard Codes Xi