CT-721

Modify Date: 2024-01-12 10:16:20

CT-721 structure	Common Name	CT-721
	CAS Number	1388710-60-8	Molecular Weight	525.04
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₉ClN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CT-721

CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities[1].

Name	CT-721

Description	CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl
Target	IC50: 21.3 nM (wild-type Bcr-Abl kinase)[1]
References	[1]. Sun Y, et al. CT-721, a Potent Bcr-Abl Inhibitor, Exhibits Excellent In Vitro and In Vivo Efficacy in the Treatment of Chronic Myeloid Leukemia. J Cancer. 2017 Aug 23;8(14):2774-2784.

Molecular Formula	C₃₀H₂₉ClN₆O
Molecular Weight	525.04

Hazard Codes	Xi