Zandelisib
Modify Date: 2025-08-25 09:54:49
Zandelisib structure
|
Common Name | Zandelisib | ||
|---|---|---|---|---|
| CAS Number | 1401436-95-0 | Molecular Weight | 576.68 | |
| Density | N/A | Boiling Point | 729.2±70.0 °C(Predicted) | |
| Molecular Formula | C31H38F2N8O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZandelisibZandelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic[1][2]. |
| Name | Zandelisib |
|---|
| Description | Zandelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic[1][2]. |
|---|---|
| Related Catalog | |
| Target |
PI3Kδ:3.5 nM (IC50) |
| In Vitro | Zandelisib inhibits PI3Ks with IC50s of 4, 976 nM, 605 nM, 817 nM and 3.5 nM for p110α, p110β, p110γ and p110δ, respectivey[1]. |
| References |
[1]. Daniel P. Gold, et al. Combination therapy. WO2019183226A1. |
| Boiling Point | 729.2±70.0 °C(Predicted) |
|---|---|
| Molecular Formula | C31H38F2N8O |
| Molecular Weight | 576.68 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
|---|