DAGLβ-IN-1

Modify Date: 2025-09-18 10:37:14

DAGLβ-IN-1 Structure
DAGLβ-IN-1 structure
Common Name DAGLβ-IN-1
CAS Number 1402612-61-6 Molecular Weight 561.60
Density N/A Boiling Point N/A
Molecular Formula C28H34F3N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DAGLβ-IN-1


DAGLβ-IN-1 is an inhibitor of diacylglycerol lipase-β (DAGLβ), serves as a versatile intermediate for the design of DAGL-tailored activity-based probes[1][2].

 Names

Name DAGLβ-IN-1

 DAGLβ-IN-1 Biological Activity

Description DAGLβ-IN-1 is an inhibitor of diacylglycerol lipase-β (DAGLβ), serves as a versatile intermediate for the design of DAGL-tailored activity-based probes[1][2].
Related Catalog
Target

DAGLβ[1]

In Vitro Diacylglycerol lipase-β (DAGLβ) is a principal biosynthetic enzyme for the endocannabinoid 2-arachidonoylglycerol (2-AG)[1].
References

[1]. Ku-Lung Hsu, et al. Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis. J Med Chem . 2013 Nov 14;56(21):8257-69.

[2]. Tiziana Bisogno, et al. Cloning of the First sn1-DAG Lipases Points to the Spatial and Temporal Regulation of Endocannabinoid Signaling in the Brain. J Cell Biol. 2003 Nov 10;163(3):463-8.

 Chemical & Physical Properties

Molecular Formula C28H34F3N5O4
Molecular Weight 561.60
InChIKey NUWWTGPNHRKNPN-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NCCCCCN(CCc1ccccc1)C(=O)n1cc(-c2ccc(OC(F)(F)F)cc2)nn1
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