Iron(II) fumarate

Modify Date: 2024-01-02 19:17:27

Iron(II) fumarate structure	Common Name	Iron(II) fumarate
	CAS Number	141-01-5	Molecular Weight	169.901
	Density	2.435	Boiling Point	N/A
	Molecular Formula	C₄H₂FeO₄	Melting Point	>280°C
	MSDS	Chinese USA	Flash Point	N/A

Use of Iron(II) fumarate

Iron(II) fumarate (Ferrous fumarate) is the iron(II) salt of fumaric acid. Iron(II) fumarate is an orally active dietary supplement and has the potential for iron deficiency anemia treatment[1][2][3].

Name	Ferrous fumarate
Synonym	More Synonyms

Description	Iron(II) fumarate (Ferrous fumarate) is the iron(II) salt of fumaric acid. Iron(II) fumarate is an orally active dietary supplement and has the potential for iron deficiency anemia treatment[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Zlotkin S, et al. Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am J Clin Nutr. 2001 Dec;74(6):791-5. [2]. Zlotkin S, et al. Use of microencapsulated iron(II) fumarate sprinkles to prevent recurrence of anaemia in infants and young children at high risk. Bull World Health Organ. 2003;81(2):108-15. [3]. Vesna D. Nikolić, et al. The synthesis and characterization of iron(II): Gluconate. Advanced technologies. 3(2) (2014) 16-24.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

References

[1]. Zlotkin S, et al. Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am J Clin Nutr. 2001 Dec;74(6):791-5.

[2]. Zlotkin S, et al. Use of microencapsulated iron(II) fumarate sprinkles to prevent recurrence of anaemia in infants and young children at high risk. Bull World Health Organ. 2003;81(2):108-15.

[3]. Vesna D. Nikolić, et al. The synthesis and characterization of iron(II): Gluconate. Advanced technologies. 3(2) (2014) 16-24.

Density	2.435
Melting Point	>280°C
Molecular Formula	C₄H₂FeO₄
Molecular Weight	169.901
Exact Mass	169.930252
PSA	52.60000
Stability	Stability

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LT1950000

CAS REGISTRY NUMBER :: 141-01-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C4-H2-O4.Fe

MOLECULAR WEIGHT :: 169.91

WISWESSER LINE NOTATION :: OV1U1VO &-FE-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting

REFERENCE :: HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants., RG 21 2XS, UK) V.1- 1981- Volume(issue)/page/year: 7,281,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,683,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 185 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,683,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,683,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1570 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 480 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 mg(Fe)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,138,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993 OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80414 No. of Facilities: 129 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 9131 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80414 No. of Facilities: 429 (estimated) No. of Industries: 3 No. of Occupations: 18 No. of Employees: 3859 (estimated) No. of Female Employees: 1728 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases	R36/37/38
Safety Phrases	S22-S36/37/39
RIDADR	NONH for all modes of transport
RTECS	LT1950000
HS Code	2917190090

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Effectiveness evaluation of the food fortification program of Costa Rica: impact on anemia prevalence and hemoglobin concentrations in women and children.

Am. J. Clin. Nutr. 101(1) , 210-7, (2015)

Food fortification is one approach for addressing anemia, but information on program effectiveness is limited.We evaluated the impact of Costa Rica's fortification program on anemia in women aged 15-4...

Rapid recovery time of hemoglobin level in female regular blood donors with ferrous fumarate and high dose of ascorbic acid supplement.

J. Med. Assoc. Thai. 96(2) , 165-71, (2013)

Iron deficiency anemia has occurred more frequently in female than male regular blood donors. Iron supplement is necessary for maintaining the hemoglobin level. A combination with ascorbic acid increa...

[Effect of iron supplementation on iron deficiency anemia of childbearing age women in Shanghai].

Wei Sheng Yan Jiu 41(1) , 51-5, (2012)

To investigate the effect of iron supplementation on iron deficiency anemia of childbearing age women, and to find out the optimal amount of iron intake for maintaining their health.74 childbearing ag...

firon

fumafer

Iron(II) fumarate

[But-2-enedioato(2-)-κO,O]iron

feostat

Fumaric acid, iron salt

ircon

Iron, [2-butenedioato(2-)-κO,κO]-

galfer

EINECS 205-447-7

Iron(2+) (2E)-2-butenedioate

2-Butenedioic acid, iron(2+) salt, (2E)- (1:1)

MFCD00058315

Ferrous Fumarate

Iron(2+) (2E)-but-2-enedioate

ferrone

feroton

fumar-f

fumar

Fumar F

cpiron

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Iron(II) fumarate
Price: ￥518.0/5g ￥608.0/10g ￥428.0/1g ￥988.0/100g
Purity: 95.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ferrous fumarate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Ferrous fumarate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Iron(II) fumarate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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