RSC 133

Modify Date: 2025-08-25 17:37:39

RSC 133 Structure
RSC 133 structure
Common Name RSC 133
CAS Number 1418131-46-0 Molecular Weight 305.331
Density 1.4±0.1 g/cm3 Boiling Point 653.7±55.0 °C at 760 mmHg
Molecular Formula C18H15N3O2 Melting Point N/A
MSDS Chinese USA Flash Point 349.1±31.5 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of RSC 133


RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells[1].

 Names

Name 3-{[(2E)-3-(1H-Indol-3-yl)-2-propenoyl]amino}benzamide
Synonym More Synonyms

 RSC 133 Biological Activity

Description RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells[1].
Related Catalog
References

[1]. Lee J, et al. A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12509-13.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 653.7±55.0 °C at 760 mmHg
Molecular Formula C18H15N3O2
Molecular Weight 305.331
Flash Point 349.1±31.5 °C
Exact Mass 305.116425
LogP 2.53
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.771

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H411
Precautionary Statements P273
RIDADR UN 3077 9 / PGIII

 Synonyms

3-{[(2E)-3-(1H-Indol-3-yl)-2-propenoyl]amino}benzamide
Benzamide, 3-[[(2E)-3-(1H-indol-3-yl)-1-oxo-2-propen-1-yl]amino]-
RSC 133
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.