N,S-Diacetylcysteamine

Modify Date: 2025-08-22 11:39:39

N,S-Diacetylcysteamine Structure
N,S-Diacetylcysteamine structure
Common Name N,S-Diacetylcysteamine
CAS Number 1420-88-8 Molecular Weight 161.22200
Density 1.114 g/cm3 Boiling Point 181-182ºC15 mm Hg(lit.),316.1ºC at 760 mmHg
Molecular Formula C6H11NO2S Melting Point 29-31ºC(lit.)
MSDS N/A Flash Point 152.4ºC

 Names

Name S-(2-acetamidoethyl) ethanethioate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.114 g/cm3
Boiling Point 181-182ºC15 mm Hg(lit.),316.1ºC at 760 mmHg
Melting Point 29-31ºC(lit.)
Molecular Formula C6H11NO2S
Molecular Weight 161.22200
Flash Point 152.4ºC
Exact Mass 161.05100
PSA 71.47000
LogP 0.79310
Vapour Pressure 0.00042mmHg at 25°C
Index of Refraction 1.485

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ6865000
CHEMICAL NAME :
Acetic acid, thio-, S-ester with N-(2-mercaptoethyl)acetamide
CAS REGISTRY NUMBER :
1420-88-8
BEILSTEIN REFERENCE NO. :
1762551
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H11-N-O2-S
MOLECULAR WEIGHT :
161.24
WISWESSER LINE NOTATION :
1VS2MV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,13,1957

 Safety Information

Safety Phrases 22-24/25
HS Code 2930909090

 Synthetic Route

~99%

N,S-Diacetylcysteamine Structure

N,S-Diacetylcys...

CAS#:1420-88-8

Literature: Veisi, Hojat; Ghorbani-Vaghei, Ramin; Eskandari, Hosna; Hemmati, Saba; Rezaei, Ardashir; Hajinazari, Somaye; Far, Mohammad Raoof Heidari; Entezari, Azam Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 2 p. 213 - 219

~95%

N,S-Diacetylcysteamine Structure

N,S-Diacetylcys...

CAS#:1420-88-8

Literature: Lee, Min S.; Qin, Guo-wei; Nakanishi, Koji; Zagorski, Michael G. Journal of the American Chemical Society, 1989 , vol. 111, # 16 p. 6234 - 6241

~72%

N,S-Diacetylcysteamine Structure

N,S-Diacetylcys...

CAS#:1420-88-8

Literature: Jenner, Matthew; Frank, Sarah; Kampa, Annette; Kohlhaas, Christoph; Poeplau, Petra; Briggs, Geoff S.; Piel, Joern; Oldham, Neil J. Angewandte Chemie - International Edition, 2013 , vol. 52, # 4 p. 1143 - 1147 Angew. Chem., 2012 , vol. 125, # 04 p. 1181 - 1185,5

~%

N,S-Diacetylcysteamine Structure

N,S-Diacetylcys...

CAS#:1420-88-8

Literature: McQuillin; Stewart Journal of the Chemical Society, 1955 , p. 2966

~%

N,S-Diacetylcysteamine Structure

N,S-Diacetylcys...

CAS#:1420-88-8

Literature: Kuhn; Quadbeck Chemische Berichte, 1951 , vol. 84, p. 844 Full Text Show Details BASF Patent: DE893795 , 1951 ; Full Text Show Details Kuhn; Quadbeck Patent: US2701256 , 1952 ;

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

S-acetyl-N-acetylcysteamine
1-acetylamino-2-acetylsulfanyl-ethane
N,S-diacetylcysteamine
EINECS 215-821-1
1-Acetylamino-2-acetylmercapto-aethan
Thioacetic acid S-2-acetamidoethyl ester
N,S-Diacetyl-2-mercaptoethylamine
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