(-)-Ketoconazole

Modify Date: 2024-01-03 18:58:49

(-)-Ketoconazole Structure
(-)-Ketoconazole structure
Common Name (-)-Ketoconazole
CAS Number 142128-57-2 Molecular Weight 531.431
Density 1.4±0.1 g/cm3 Boiling Point 753.4±60.0 °C at 760 mmHg
Molecular Formula C26H28Cl2N4O4 Melting Point N/A
MSDS N/A Flash Point 409.4±32.9 °C

 Use of (-)-Ketoconazole


(-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).

 Names

Name Levoketoconazole
Synonym More Synonyms

 (-)-Ketoconazole Biological Activity

Description (-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).
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 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 753.4±60.0 °C at 760 mmHg
Molecular Formula C26H28Cl2N4O4
Molecular Weight 531.431
Flash Point 409.4±32.9 °C
Exact Mass 530.148743
LogP 3.55
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.642

 Synonyms

KETOCONAZOLE, (2S,4R)-
MFCD25509433
4594
COR-003
(2S,4R)-ketoconazole
1-[4-(4-{[(2S,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-1-piperazinyl]ethanone
2DJ8R0NT7K
Ethanone, 1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]-
R9400W927I
UNII:R9400W927I
10206
Levoketoconazole
MFCD00058579
EINECS 265-667-4
UNII-2DJ8R0NT7K
(-)-Ketoconazole
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