(±)-cis-N-Boc-4-fluorocyclohexylamine
Modify Date: 2025-08-23 15:18:17
(±)-cis-N-Boc-4-fluorocyclohexylamine structure
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Common Name | (±)-cis-N-Boc-4-fluorocyclohexylamine | ||
|---|---|---|---|---|
| CAS Number | 1422966-97-9 | Molecular Weight | 217.28 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 297.4±29.0 °C at 760 mmHg | |
| Molecular Formula | C11H20FNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 133.6±24.3 °C | |
Use of (±)-cis-N-Boc-4-fluorocyclohexylamineDescription The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexaneamine allows for the straightforward application in organic synthesis, after simple deprotection. It has been shown, that this compound can be used for the preparation of fluorinated analogs of Lomustine and Bromhexine. Description The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexaneamine allows for the straightforward application in organic synthesis, after simple deprotection. It has been shown, that this compound can be used for the preparation of fluorinated analogs of Lomustine and Bromhexine. |
| Name | (±)-cis-N-Boc-4-fluorocyclohexylamine |
|---|---|
| Synonym | More Synonyms |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 297.4±29.0 °C at 760 mmHg |
| Molecular Formula | C11H20FNO2 |
| Molecular Weight | 217.28 |
| Flash Point | 133.6±24.3 °C |
| Exact Mass | 217.147812 |
| LogP | 2.59 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.452 |
| 2-Methyl-2-propanyl (cis-4-fluorocyclohexyl)carbamate |
| Carbamic acid, N-(cis-4-fluorocyclohexyl)-, 1,1-dimethylethyl ester |
| MFCD18434519 |