MK-8189
Modify Date: 2024-01-18 19:06:50
MK-8189 structure
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Common Name | MK-8189 | ||
|---|---|---|---|---|
| CAS Number | 1424371-93-6 | Molecular Weight | 382.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H22N6OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK-8189MK-8189 is a potent, orally active and selective PDE10A inhibitor with a Ki value of 29 pM. MK-8189 can be used in research of schizophrenia[1]. |
| Name | MK-8189 |
|---|
| Description | MK-8189 is a potent, orally active and selective PDE10A inhibitor with a Ki value of 29 pM. MK-8189 can be used in research of schizophrenia[1]. |
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| Related Catalog | |
| Target |
PDE10A:29 pM (Ki) |
| In Vivo | MK-8189 (0.25-0.75 mg/kg; po) 以剂量依赖的方式减弱大鼠的运动活动。 Animal Model: Male Wistar-Hannover rats[1] Dosage: 0.25, 0.5, and 0.75 mg/kg Administration: Oral administration Result: Improved identification ability relative to the vector handling animal. |
| References |
| Molecular Formula | C19H22N6OS |
|---|---|
| Molecular Weight | 382.48 |