Azt-pmap
Modify Date: 2024-01-09 09:52:56
Azt-pmap structure
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Common Name | Azt-pmap | ||
|---|---|---|---|---|
| CAS Number | 142629-81-0 | Molecular Weight | 508.42200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H25N6O8P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Azt-pmapAzt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity[1]. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection[2]. |
| Name | So221 |
|---|---|
| Synonym | More Synonyms |
| Description | Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity[1]. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection[2]. |
|---|---|
| Related Catalog | |
| Target |
HIV-1 |
| In Vitro | Azt-pmap shows anti-HIV-1 activities in infected C8166 and JM cells with EC50s of 0.08 and0.32 μM, respectively. Azt-pmap displays toxicities in infected C8166 and JM cells with TC50s of 500 μM, respectively. Azt-pmap inhibits virus replication[1]. |
| References |
| Molecular Formula | C20H25N6O8P |
|---|---|
| Molecular Weight | 508.42200 |
| Exact Mass | 508.14700 |
| PSA | 197.51000 |
| LogP | 2.00986 |
| (S)-2-{[(2S,3S,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino}-propionic acid methyl ester |