Triptoquinone B

Modify Date: 2023-10-11 08:39:53

Triptoquinone B structure	Common Name	Triptoquinone B
	CAS Number	142937-50-6	Molecular Weight	330.418
	Density	1.2±0.1 g/cm3	Boiling Point	475.4±45.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	255.4±25.2 °C

Use of Triptoquinone B

Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].

Name	Triptoquinone B
Synonym	More Synonyms

Description	Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IL-1
References	[1]. Takaishi Y, et, al. Triptoquinone A and B novel interleukin-1 inhibitors from Tripterygium wilfordii var Regeli. Tetrahedron Letters. 1992 Nov; 33(47): 7177-7180. [2]. Wang XD, et, al. Terpene alkaloids from Tripterygium wilfordii. J Asian Nat Prod Res. 2005 Oct;7(5):755-9.

Density	1.2±0.1 g/cm3
Boiling Point	475.4±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₆O₄
Molecular Weight	330.418
Flash Point	255.4±25.2 °C
Exact Mass	330.183105
PSA	71.44000
LogP	2.77
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.558