Neotuberostemonine

Modify Date: 2024-01-02 17:44:27

Neotuberostemonine structure	Common Name	Neotuberostemonine
	CAS Number	143120-46-1	Molecular Weight	375.502
	Density	1.2±0.1 g/cm3	Boiling Point	554.2±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₃NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	289.0±30.1 °C

Use of Neotuberostemonine

Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[1].

Name	(2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4 -methyl-5-oxotetrahydro-2-furanyl]dodecahydroazepino[3,2,1-hi]fur o[3,2-e]indol-10(2H)-one
Synonym	More Synonyms

Description	Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Xiang J, et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages. Int Immunopharmacol. 2016 Jul;36:158-164.

Density	1.2±0.1 g/cm3
Boiling Point	554.2±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₃₃NO₄
Molecular Weight	375.502
Flash Point	289.0±30.1 °C
Exact Mass	375.240967
PSA	55.84000
LogP	2.28
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.556

Hazard Codes	Xi

Tuberostemonin

(2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4-methyl-5-oxotetrahydro-2-furanyl]dodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one

Tubastatin A

Azepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one, 8-ethyldodecahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-

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Neotuberostemonine