kresoxim-methyl

Modify Date: 2024-01-01 23:41:03

kresoxim-methyl Structure
kresoxim-methyl structure
Common Name kresoxim-methyl
CAS Number 143390-89-0 Molecular Weight 313.348
Density 1.1±0.1 g/cm3 Boiling Point 429.4±47.0 °C at 760 mmHg
Molecular Formula C18H19NO4 Melting Point 98-100°C
MSDS Chinese USA Flash Point 171.2±23.7 °C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

 Use of kresoxim-methyl


Kresoxim-methyl (BAS 490 F), a Strobilurin-based fungicide, inhibits the respiration at the complex III (cytochrome bc1 complex). Kresoxim-methyl binds to complex III from yeast with an apparent Kd of 0.07 μM proving a high affinity for this enzyme[1][2].

 Names

Name kresoxim-methyl
Synonym More Synonyms

 kresoxim-methyl Biological Activity

Description Kresoxim-methyl (BAS 490 F), a Strobilurin-based fungicide, inhibits the respiration at the complex III (cytochrome bc1 complex). Kresoxim-methyl binds to complex III from yeast with an apparent Kd of 0.07 μM proving a high affinity for this enzyme[1][2].
Related Catalog
In Vitro Kresoxim-methyl affects antioxidant response, mitochondrial function and motility of neuroblastoma N2a cells upon 24h exposure[3].
References

[1]. Roehl F. Binding of BAS 490 F to bc1-complex from yeast. Biochem Soc Trans. 1994;22(1):64S.

[2]. Köhle H, et al. Biokinetic properties of BAS 490 F and some related compounds. Biochem Soc Trans. 1994;22(1):65S.

[3]. Flampouri E, et al. Strobilurin fungicide kresoxim-methyl effects on a cancerous neural cell line: oxidant/antioxidant responses and in vitro migration. Toxicol Mech Methods. 2018;28(9):709-716.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 429.4±47.0 °C at 760 mmHg
Melting Point 98-100°C
Molecular Formula C18H19NO4
Molecular Weight 313.348
Flash Point 171.2±23.7 °C
Exact Mass 313.131409
PSA 57.12000
LogP 4.34
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.531
Storage condition 0-6°C

 Safety Information

Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H351-H410
Precautionary Statements P273-P281-P501
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful
Risk Phrases R40;R50/53
Safety Phrases S2-S36/37-S60-S61
RIDADR UN3077 9/PG 3
Packaging Group III
HS Code 2925290013

 Synthetic Route

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kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: WO2008/125592 A1, ; Page/Page column 13 ;

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kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: RALLIS INDIA LTD.; KAMARAJ, Pasumpon; SATAM, Vijay, Shrikant; AJJANNA, Mahalingappa, Sridhara; NANDI, Tapaskumar; BOBADE, Anna; SHINDE, Ravindra; NAIK, Parag; MOHITE, Dhanaji; KADAM, Subhash; HINDUPUR, Rama, Mohan; PATI, Hari, Narayan; MANE, Avinash; VADIRAJ, Suphala, Gopinath; VENKATESH, Prabhu, Moodbidri Patent: WO2013/144924 A1, 2013 ; Location in patent: Page/Page column 28; 36 ;

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kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: US5354883 A1, ;

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kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: US5221762 A1, ;

~64%

kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: Tetrahedron, , vol. 55, # 37 p. 11343 - 11364

~%

kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: Tetrahedron, , vol. 55, # 37 p. 11343 - 11364

~%

kresoxim-methyl Structure

kresoxim-methyl

CAS#:143390-89-0

Literature: Tetrahedron, , vol. 55, # 37 p. 11343 - 11364

 Customs

HS Code 2925290013
Summary HS: 2925290013 (e)-methyl 2-(methoxyimino)-2-(2-((o-tolyloxy)methyl)phenyl)acetate Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:S(Registration certificate of import and export) Lowest tariff:6.5% General tariff:30.0%

 Articles3

More Articles
Use of fresh and cryopreserved hepatocytes to study the metabolism of pesticides in food-producing animals and rats.

Xenobiotica 26(8) , 803-11, (1996)

1. The possibility of using hepatocytes from food-producing animals in order to determine the metabolic routes of pesticides has been studied using a strobilurin fungicide (BAS 490 F). Hepatocytes sus...

Biokinetic properties of BAS 490 F and some related compounds.

Biochem. Soc. Trans. 22(1) , 65S, (1994)

Binding of BAS 490 F to bc1-complex from yeast.

Biochem. Soc. Trans. 22(1) , 64S, (1994)

 Synonyms

1ONUYVO1&R B1OR B1 &&E Form
(2E)-(Méthoxyimino){2-[(2-méthylphénoxy)méthyl]phényl}acétate de méthyle
(E)-Methyl α-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetate
Methyl (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetate
methyl (E)-methoxyimino[α-(o-tolyloxy)-o-tolyl]acetate
methyl (αE)-α-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetate
MFCD00871777
methyl (2E)-(methoxyimino){[(2-methylphenoxy)methyl]phenyl}acetate
kresoxim-methyl
Benzeneacetic acid, α-(methoxyimino)-2-[(2-methylphenoxy)methyl]-, methyl ester, (αE)-
Methyl-(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetat
Methyl (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoate
methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate
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