Antibiotic 1142

Modify Date: 2025-08-21 14:31:16

Antibiotic 1142 structure	Common Name	Antibiotic 1142
	CAS Number	1438-30-8	Molecular Weight	430.46400
	Density	1.52g/cm3	Boiling Point	544.74°C (rough estimate)
	Molecular Formula	C₁₈H₂₆N₁₀O₃	Melting Point	171-173℃
	MSDS	N/A	Flash Point	N/A

Use of Antibiotic 1142

Netropsin is a basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research. Netropsin is a polyamide with antibiotic and antiviral activity. It has been shown that Netropsin is active both against Gram-positive bacteria and Gram-negative bacteria.

Name	netropsin
Synonym	More Synonyms

Density	1.52g/cm3
Boiling Point	544.74°C (rough estimate)
Melting Point	171-173℃
Molecular Formula	C₁₈H₂₆N₁₀O₃
Molecular Weight	430.46400
Exact Mass	430.21900
PSA	208.93000
LogP	1.62120
Appearance of Characters	powder \| faint yellow
Vapour Pressure	1.75E-23mmHg at 25°C
Index of Refraction	1.6500 (estimate)
Storage condition	−20°C
Water Solubility	H2O: 1 mg/mL

Antibiotic 1142 MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DW2973000

CHEMICAL NAME :: N,4'-Bi(pyrrole-2-carboxamide), N'-(2-carbamoylethyl)-4-((2-guanidinoacetimidoyl)amin o)-1,1'- dimethyl-

CAS REGISTRY NUMBER :: 1438-30-8

BEILSTEIN REFERENCE NO. :: 0376913

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C18-H26-N10-O3

MOLECULAR WEIGHT :: 430.54

WISWESSER LINE NOTATION :: T5NJ A1 BVM2VZ EMV- BT5NJ A1 DMYUM&1MYZUM

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 17 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 500 umol/L

REFERENCE :: MLBRBU Molecular Biology Reports. (Dr. W. Junk Pub., POB 163, 3300 AD Dordrect, Netherlands) V.1- 1973- Volume(issue)/page/year: 2,135,1975

Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	DW2973000

4-{4-[(N-carbamimidoyl-glycyl)-amino]-1-methyl-pyrrole-2-carbonylamino}-1-methyl-pyrrole-2-carboxylic acid-(2-carbamimidoyl-ethylamide)

t1384

Netropsin dihydrochloride

ia887

4-{4-[(N-Carbamimidoyl-glycyl)-amino]-1-methyl-pyrrol-2-carbonylamino}-1-methyl-pyrrol-2-carbonsaeure-(2-carbamimidoyl-aethylamid)

ch-777-a

Congocidin Sinanomycin

congocidin

ultrapuregrade

2814-a

antibiotic1142

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Antibiotic 1142
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Antibiotic 1142
Price: ￥3478.0/25mg ￥1058.0/5mg
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Antibiotic 1142
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Antibiotic 1142
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Antibiotic 1142

Use of Antibiotic 1142

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.