ONO4059 hydrochloride
Modify Date: 2024-01-06 11:52:45
ONO4059 hydrochloride structure
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Common Name | ONO4059 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1439901-97-9 | Molecular Weight | 490.941 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H23ClN6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ONO4059 hydrochlorideTirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. |
| Name | ONO-4059 |
|---|---|
| Synonym | More Synonyms |
| Description | Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.2 nM (BTK)[1]. |
| References |
| Molecular Formula | C25H23ClN6O3 |
|---|---|
| Molecular Weight | 490.941 |
| Exact Mass | 490.152008 |
| Storage condition | -20℃ |
| Hazard Codes | N |
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| 8H-Purin-8-one, 6-amino-7,9-dihydro-9-[(3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-, hydrochloride (1:1) |
| 6-Amino-9-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride (1:1) |
| ONO4059 hydrochloride |
| ONO-4059(HCl salt) |
| ONO-4059 (hydrochloride) |