Mongersen

Modify Date: 2025-08-26 09:33:06

Mongersen Structure
Mongersen structure
Common Name Mongersen
CAS Number 1443994-46-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mongersen


Mongersen is a 21-mer phosphorothioate antisense oligonucleotide targeting the mRNA of the Smad7 protein, thus leading to suppression of TGF-β1 pathways and remission of Crohn's disease.

 Names

Name Mongersen

 Mongersen Biological Activity

Description Mongersen is a 21-mer phosphorothioate antisense oligonucleotide targeting the mRNA of the Smad7 protein, thus leading to suppression of TGF-β1 pathways and remission of Crohn's disease.
Related Catalog
References

[1]. Monteleone G, Neurath MF, Ardizzone S, et al. Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease. N Engl J Med. 2015;372(12):1104-1113.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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