Landiolol Hydrochloride

Modify Date: 2025-08-26 19:45:25

Landiolol Hydrochloride structure	Common Name	Landiolol Hydrochloride
	CAS Number	144481-98-1	Molecular Weight	546.053
	Density	1.201g/cm3	Boiling Point	727.5ºC at 760mmHg
	Molecular Formula	C₂₅H₄₀ClN₃O₈	Melting Point	122-127ºC
	MSDS	N/A	Flash Point	393.8ºC

Use of Landiolol Hydrochloride

Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist[1].

Name	Landiolol hydrochloride
Synonym	More Synonyms

Description	Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	beta-adrenergic receptor[1]
References	[1]. Atarashi H, et al. Pharmacokinetics of landiolol hydrochloride, a new ultra-short-acting beta-blocker, in patients with cardiac arrhythmias. Clin Pharmacol Ther. 2000 Aug;68(2):143-50. [2]. Okajima M, et al. Landiolol, an ultra-short-acting β1-blocker, is useful for managing supraventricular tachyarrhythmias in sepsis. World J Crit Care Med. 2015 Aug 4;4(3):251-7.

Density	1.201g/cm3
Boiling Point	727.5ºC at 760mmHg
Melting Point	122-127ºC
Molecular Formula	C₂₅H₄₀ClN₃O₈
Molecular Weight	546.053
Flash Point	393.8ºC
Exact Mass	545.250366
PSA	127.82000
LogP	2.37760
Vapour Pressure	3.24E-22mmHg at 25°C

RTECS	DA8346700

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Landiolol Hydro...

CAS#:144481-98-1

Literature: Procos S.p.A.; Garavaglia, Fabio; Roletto, Jacopo; Paissoni, Paolo Patent: EP2687521 A1, 2014 ; Location in patent: Paragraph 0053; 0054; 0055; 0056; 0057 ;

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Landiolol Hydro...

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Literature: Procos S.p.A.; Garavaglia, Fabio; Roletto, Jacopo; Paissoni, Paolo Patent: EP2687521 A1, 2014 ; Location in patent: Paragraph 0051; 0052 ;

4-Hydroxybenzen...

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Landiolol Hydro...

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Literature: EP2687521 A1, ;

((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((S)-2-hydroxy-3-(2-(morpholine-4-carboxamido)ethylamino)propoxy)phenyl)propanoate hydrochloride

[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate hydrochloride

(-)-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-3-[4-[(S)-2-hydroxy-3-(2-morpholinocarbonylamino)ethylamino]propoxy]phenylpropionic acid hydrochloride

(-)-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(S)-2-hydroxy-3-(2-(morpholinocarbonylamino)ethylamino)propoxy]phenyl]propionate monohydrochloride

Benzenepropanoic acid,4-(2-hydroxy-3-((2-((4-morpholinylcarbonyl)amino)ethyl)amino)propoxy)-,(2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester,(S-(R*,R*))-,hydrochloride

Landiololhydrochloride

Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester, hydrochloride (1:1)

Ono 1101 hydrochloride

2,2-dimethyl-1,3-dioxolan-4S-yl-methyl 3-[P-{3-{(2-(morpholinocarbonylamino)ethyl)amino}-2S-hydroxypropoxy}phenyl] propionate hydrochloride

[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]methyl 3-{4-[(2S)-2-hydroxy-3-({2-[(4-morpholinylcarbonyl)amino]ethyl}amino)propoxy]phenyl}propanoate hydrochloride (1:1)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Landiolol Hydrochloride
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Landiolol Hydrochloride
Price: $200.0/100mg $400.0/250mg $800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Landiolol Hydrochloride
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Landiolol hydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: Landiolol Hydrochloride
Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg
Purity: 98.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Landiolol Hydrochloride
Price: ￥Inquiry/1kg ￥Inquiry/25kg ￥Inquiry/200kg
Purity: 99.8%
Delivery: 3 Day
Contact: Wang Jie
Email: 3096638339@qq.com

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Price: ￥500/5 mg

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Landiolol Hydrochloride

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