NYC-488

Modify Date: 2025-08-27 11:17:48

NYC-488 Structure
NYC-488 structure
Common Name NYC-488
CAS Number 1448429-06-8 Molecular Weight 460.44
Density N/A Boiling Point N/A
Molecular Formula C19H17FN6O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NYC-488


Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM)[1].

 Names

Name Calpain Inhibitor-1

 NYC-488 Biological Activity

Description Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM)[1].
Related Catalog
References

[1]. Schiefer IT, Tapadar S, Litosh V, et al. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. J Med Chem. 2013;56(15):6054-6068.

 Chemical & Physical Properties

Molecular Formula C19H17FN6O5S
Molecular Weight 460.44
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