NYC-488

Modify Date: 2024-01-12 23:27:29

Use of NYC-488

Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM)[1].

Name	Calpain Inhibitor-1

Description	Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Research Areas >> Neurological Disease
References	[1]. Schiefer IT, Tapadar S, Litosh V, et al. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. J Med Chem. 2013;56(15):6054-6068.

Molecular Formula	C₁₉H₁₇FN₆O₅S
Molecular Weight	460.44

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