UM729
Modify Date: 2025-08-23 19:54:43
UM729 structure
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Common Name | UM729 | ||
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| CAS Number | 1448723-60-1 | Molecular Weight | 367.44 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 611.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H25N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 323.4±31.5 °C | |
Use of UM729UM729 is a new pyrimidoindole, which has an additive effect with AhR antagonists in preventing differentiation in most AML specimens; collaborates with Ahr suppressors in preventing AML cell differentiation.IC50 value:Target: SR1 and UM729 can be implemented as a standardized supplement in culture media and will pave the way for studies of self-renewal mechanisms and for the identification of new antileukemic drugs through cell-based assays for primary human AML cells. |
| Name | Methyl 4-{[3-(1-piperidinyl)propyl]amino}-1H-pyrimido[4,5-b]indole-7-carboxylate |
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| Synonym | More Synonyms |
| Description | UM729 is a new pyrimidoindole, which has an additive effect with AhR antagonists in preventing differentiation in most AML specimens; collaborates with Ahr suppressors in preventing AML cell differentiation.IC50 value:Target: SR1 and UM729 can be implemented as a standardized supplement in culture media and will pave the way for studies of self-renewal mechanisms and for the identification of new antileukemic drugs through cell-based assays for primary human AML cells. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 611.1±55.0 °C at 760 mmHg |
| Molecular Formula | C20H25N5O2 |
| Molecular Weight | 367.44 |
| Flash Point | 323.4±31.5 °C |
| Exact Mass | 367.200836 |
| LogP | 4.10 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.677 |
| 9H-Pyrimido[4,5-b]indole-7-carboxylic acid, 4-[[3-(1-piperidinyl)propyl]amino]-, methyl ester |
| Methyl 4-{[3-(1-piperidinyl)propyl]amino}-1H-pyrimido[4,5-b]indole-7-carboxylate |
| UM729 |