Name | Methyl 4-{[3-(1-piperidinyl)propyl]amino}-1H-pyrimido[4,5-b]indole-7-carboxylate |
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Synonyms |
9H-Pyrimido[4,5-b]indole-7-carboxylic acid, 4-[[3-(1-piperidinyl)propyl]amino]-, methyl ester
Methyl 4-{[3-(1-piperidinyl)propyl]amino}-1H-pyrimido[4,5-b]indole-7-carboxylate UM729 |
Description | UM729 is a new pyrimidoindole, which has an additive effect with AhR antagonists in preventing differentiation in most AML specimens; collaborates with Ahr suppressors in preventing AML cell differentiation.IC50 value:Target: SR1 and UM729 can be implemented as a standardized supplement in culture media and will pave the way for studies of self-renewal mechanisms and for the identification of new antileukemic drugs through cell-based assays for primary human AML cells. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 611.1±55.0 °C at 760 mmHg |
Molecular Formula | C20H25N5O2 |
Molecular Weight | 367.44 |
Flash Point | 323.4±31.5 °C |
Exact Mass | 367.200836 |
LogP | 4.10 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.677 |