Cu(II) protoporphyrin IX

Modify Date: 2024-01-28 09:57:42

Cu(II) protoporphyrin IX structure	Common Name	Cu(II) protoporphyrin IX
	CAS Number	14494-37-2	Molecular Weight	624.18800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₃₂CuN₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cu(II) protoporphyrin IX

Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair[1][2][3].

Name	3-[(1Z,4Z,10Z,14Z)-18-(2-carboxyethyl)-7,12-bis(ethenyl)-3,8,13,17-tetramethylporphyrin-21,22,23,24-tetraid-2-yl]propanoic acid,copper
Synonym	More Synonyms

Description	Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Jozkowicz A, et al. Heme oxygenase-1 in tumors: is it a false friend?. Antioxid Redox Signal. 2007;9(12):2099-2117. [2]. Abraham NG, et al. Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med. 2005;39(1):1-25. [3]. Kim DH, et al. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther. 2008;325(3):833-840.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Jozkowicz A, et al. Heme oxygenase-1 in tumors: is it a false friend?. Antioxid Redox Signal. 2007;9(12):2099-2117.

[2]. Abraham NG, et al. Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med. 2005;39(1):1-25.

[3]. Kim DH, et al. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther. 2008;325(3):833-840.

Molecular Formula	C₃₄H₃₂CuN₄O₄
Molecular Weight	624.18800
Exact Mass	623.17200
PSA	94.32000
LogP	2.32230

Protoporphyrin IX

CAS#:553-12-8

Copper(II) acetate

CAS#:142-71-2

Cu(II) protopor...

CAS#:14494-37-2

Literature: Fischer, H.; Puetzer, B. Zeitschrift fuer Physiologische Chemie, 1926 , vol. 154, p. 39 - 63 Full Text Show Details Gmelin Handbook: Cu: MVol.B4, 133, page 1739 - 1741

Protoporphyrin IX

CAS#:553-12-8

Cu(II) protopor...

CAS#:14494-37-2

Literature: Bark, Ki-Min; Yang, Jeong-Im; Lee, Ho-Suk; Lee, Jee-Bum; Park, Chul-Ho; Park, Hyoung-Ryun Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 6 p. 1633 - 1637

Precursor 2
CAS#:553-12-8 Protoporphyrin IX CAS#:142-71-2 Copper(II) acetate
DownStream 0

copper protoporphyrin IX

Cu(II) protoporphyrin IX

Use of Cu(II) protoporphyrin IX

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Cu(II) protoporphyrin IX Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms