FGIN-1-43

Modify Date: 2023-02-01 22:52:28

FGIN-1-43 Structure
FGIN-1-43 structure
Common Name FGIN-1-43
CAS Number 145040-29-5 Molecular Weight 487.50
Density 1.143g/cm3 Boiling Point 648.5ºC at 760 mmHg
Molecular Formula C28H36Cl2N2O Melting Point N/A
MSDS N/A Flash Point 346ºC

 Use of FGIN-1-43


FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety[1].

 Names

Name 2-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
Synonym More Synonyms

 FGIN-1-43 Biological Activity

Description FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety[1].
Related Catalog
References

[1]. Guillon J, et al. Synthesis and preliminary behavioural evaluation in mice of new 3-aryl-3-pyrrol-1-ylpropanamides, analogues of FGIN-1-27 and FGIN-1-43. J Pharm Pharmacol. 2001 Nov;53(11):1561-8.  

 Chemical & Physical Properties

Density 1.143g/cm3
Boiling Point 648.5ºC at 760 mmHg
Molecular Formula C28H36Cl2N2O
Molecular Weight 487.50
Flash Point 346ºC
Exact Mass 486.22000
PSA 36.10000
LogP 8.67340
Vapour Pressure 1.05E-16mmHg at 25°C
Index of Refraction 1.579
Storage condition -20°C

 Synonyms

FGIN-1-43
Tocris-0659
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