Tiagabine hydrochloride hydrate

Modify Date: 2024-01-16 03:41:37

Tiagabine hydrochloride hydrate Structure
Tiagabine hydrochloride hydrate structure
Common Name Tiagabine hydrochloride hydrate
CAS Number 145821-57-4 Molecular Weight 430.02
Density N/A Boiling Point N/A
Molecular Formula C20H28ClNO3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tiagabine hydrochloride hydrate


Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].

 Names

Name Tiagabine hydrochloride hydrate

 Tiagabine hydrochloride hydrate Biological Activity

Description Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].
Related Catalog
References

[1]. Braestrup C, et al. (R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier. J Neurochem. 1990 Feb;54(2):639-47.

 Chemical & Physical Properties

Molecular Formula C20H28ClNO3S2
Molecular Weight 430.02
Storage condition 2-8℃

 Safety Information

RIDADR NONH for all modes of transport
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