CB-618

Modify Date: 2024-03-03 19:13:43

CB-618 Structure
CB-618 structure
Common Name CB-618
CAS Number 1463520-70-8 Molecular Weight 290.253
Density 1.9±0.1 g/cm3 Boiling Point N/A
Molecular Formula C8H10N4O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CB-618


CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.

 Names

Name (2S,5R)-2-(1,3,4-Oxadiazol-2-yl)-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octan-7-one
Synonym More Synonyms

 CB-618 Biological Activity

Description CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.
References References 1. VanScoy BD, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3891-6. 2. Ambrose PG, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00630-17. View Related Products by Target Bacterial

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Molecular Formula C8H10N4O6S
Molecular Weight 290.253
Exact Mass 290.032104
LogP -2.45
Index of Refraction 1.685

 Synonyms

1,6-Diazabicyclo[3.2.1]octan-7-one, 2-(1,3,4-oxadiazol-2-yl)-6-(sulfooxy)-, (2S,5R)-
(2S,5R)-2-(1,3,4-Oxadiazol-2-yl)-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octan-7-one