Selenomethionine

Modify Date: 2024-01-05 13:42:35

Selenomethionine Structure
Selenomethionine structure
Common Name Selenomethionine
CAS Number 1464-42-2 Molecular Weight 196.106
Density N/A Boiling Point 320.8±37.0 °C at 760 mmHg
Molecular Formula C5H11NO2Se Melting Point 267-269ºC
MSDS USA Flash Point 147.8±26.5 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

 Use of Selenomethionine


Selenomethionine is a naturally occurring amino acid containing selenium, is a common natural food source of selenium.

 Names

Name selenomethionine
Synonym More Synonyms

 Selenomethionine Biological Activity

Description Selenomethionine is a naturally occurring amino acid containing selenium, is a common natural food source of selenium.
Related Catalog

 Chemical & Physical Properties

Boiling Point 320.8±37.0 °C at 760 mmHg
Melting Point 267-269ºC
Molecular Formula C5H11NO2Se
Molecular Weight 196.106
Flash Point 147.8±26.5 °C
Exact Mass 196.995499
PSA 63.32000
LogP -0.65
Vapour Pressure 0.0±1.5 mmHg at 25°C
Storage condition −20°C
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ES7100000
CHEMICAL NAME :
Butyric acid, 2-amino-4-(methylselenyl)-
CAS REGISTRY NUMBER :
1464-42-2
LAST UPDATED :
199712
DATA ITEMS CITED :
29
MOLECULAR FORMULA :
C5-H11-N-O2-Se
MOLECULAR WEIGHT :
196.13
WISWESSER LINE NOTATION :
QVYZ2-SE-1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
22 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Cardiac - other changes Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intracervical
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - pig
DOSE/DURATION :
7450 ug/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Gastrointestinal - nausea or vomiting
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
37 mg/kg/12W-C
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
14710 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
80 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 224,503,1989 *** REVIEWS *** ACGIH TLV-TWA 0.2 mg(Se)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.2 mg(Se)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,224,1971 OSHA PEL (Gen Indu):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-BELGIUM:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-DENMARK:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-FINLAND:TWA 0.1 mg(Se)/m3;STEL 0.3 mg(Se)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-HUNGARY:STEL 0.1 mg(Se)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-POLAND:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-TURKEY:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Se)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301 + H331-H373-H410
Precautionary Statements P261-P273-P301 + P310-P311-P501
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R23/25;R33;R50/53
Safety Phrases S20/21-S28-S45-S60-S61
RIDADR UN 3283
RTECS ES7110000
HS Code 2930909090

 Synthetic Route

~%

Selenomethionine Structure

Selenomethionine

CAS#:1464-42-2

Selenomethionine Structure

Selenomethionine

CAS#:1464-42-2

Literature: Synthetic Communications, , vol. 19, # 7,8 p. 1203 - 1210

~%

Selenomethionine Structure

Selenomethionine

CAS#:1464-42-2

Selenomethionine Structure

Selenomethionine

CAS#:1464-42-2

Literature: Synthetic Communications, , vol. 19, # 7,8 p. 1203 - 1210

~%

Selenomethionine Structure

Selenomethionine

CAS#:1464-42-2

Selenomethionine Structure

Selenomethionine

CAS#:1464-42-2

Literature: Synthetic Communications, , vol. 19, # 7,8 p. 1203 - 1210

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles43

More Articles
Determination of selenium and its compounds in marine organisms.

J. Trace Elem. Med. Biol. 29 , 91-8, (2015)

In this study, we investigate the type and quantity of selenium compounds in fish and marine organisms, using ion-pair reversed phase LC–ICP-MS, developed and applied for the analysis of Atlantic cod,...

Influence of Dietary Selenium Species on Selenoamino Acid Levels in Rainbow Trout.

J. Agric. Food Chem. 63 , 6484-92, (2015)

Two forms of selenium (Se) supplementation of fish feeds were compared in two different basal diets. A 12-week feeding trial was performed with rainbow trout fry using either a plant-based or a fish m...

Antitumor activity of an enzyme prodrug therapy targeted to the breast tumor vasculature.

Cancer Invest. 31(8) , 505-10, (2013)

The L-methioninase-annexin V/selenomethionine enzyme prodrug system, designed to target the tumor vasculature and release the methylselenol anticancer drug in the tumor, was tested in mice with implan...

 Synonyms

EINECS 215-977-0
Seleno-DL-methionine
2-Amino-4-(methylselanyl)butanoic acid
DL-Selenomethionine
2-Amino-4-(methylseleno)butyric Acid
Butanoic acid, 2-amino-4-(methylseleno)-
Selenomethionine
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