diphenylpyraline
Modify Date: 2024-01-08 15:50:22
diphenylpyraline structure
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Common Name | diphenylpyraline | ||
|---|---|---|---|---|
| CAS Number | 147-20-6 | Molecular Weight | 281.39200 | |
| Density | 1.08 g/cm3 | Boiling Point | 378.7ºC at 760 mmHg | |
| Molecular Formula | C19H23NO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 111.6ºC | |
Use of diphenylpyralineDiphenylpyraline is a potent histamine H1 receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al[1]. |
| Name | diphenylpyraline |
|---|---|
| Synonym | More Synonyms |
| Description | Diphenylpyraline is a potent histamine H1 receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al[1]. |
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| Related Catalog | |
| Target |
H1 Receptor |
| In Vitro | Diphenylpyraline (10 μM) markedly inhibits dopamine uptakein mouse nucleus accumbens slices[2]. |
| In Vivo | Diphenylpyraline (intraperitoneal injection; 5-10 mg/kg) elevates extracellular dopamine levels (~200%) in mouse nucleus accumbens and induces locomotor activation in mice[2]. Animal Model: C57BL/6 mice[2] Dosage: 5-10 mg/kg Administration: Intraperitoneal injection Result: Had psychostimulant properties. |
| References |
| Density | 1.08 g/cm3 |
|---|---|
| Boiling Point | 378.7ºC at 760 mmHg |
| Molecular Formula | C19H23NO |
| Molecular Weight | 281.39200 |
| Flash Point | 111.6ºC |
| Exact Mass | 281.17800 |
| PSA | 12.47000 |
| LogP | 3.82470 |
| Vapour Pressure | 6.18E-06mmHg at 25°C |
| Index of Refraction | 1.587 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Hazard Codes | Xn |
|---|---|
| RIDADR | UN 3249 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2933399090 |
CAS#:106-52-5
CAS#:776-74-9
CAS#:90-99-3
CAS#:58258-01-8
CAS#:65214-84-8| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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