NITD-304

Modify Date: 2024-04-03 15:32:28

NITD-304 Structure
NITD-304 structure
 Common Name NITD-304
CAS Number 1473450-60-0 Molecular Weight 339.259
Density 1.3±0.1 g/cm3 Boiling Point 551.5±45.0 °C at 760 mmHg
Molecular Formula C17H20Cl2N2O Melting Point N/A
MSDS N/A Flash Point 287.3±28.7 °C

 Use of NITD-304


NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv; shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb; demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.

 Names

Name 4,6-Dichloro-N-(4,4-dimethylcyclohexyl)-1H-indole-2-carboxamide
Synonym More Synonyms

 NITD-304 Biological Activity

Description NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv; shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb; demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.
References References 1. Rao SP, et al. Sci Transl Med. 2013 Dec 4;5(214):214ra168. View Related Products by Target Bacterial

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 551.5±45.0 °C at 760 mmHg
Molecular Formula C17H20Cl2N2O
Molecular Weight 339.259
Flash Point 287.3±28.7 °C
Exact Mass 338.095276
LogP 6.10
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.620

 Synonyms

4,6-Dichloro-N-(4,4-dimethylcyclohexyl)-1H-indole-2-carboxamide
MFCD28502067
1H-Indole-2-carboxamide, 4,6-dichloro-N-(4,4-dimethylcyclohexyl)-
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Chemsrc provides NITD-304(CAS#:1473450-60-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of NITD-304 are included as well.>> amp version: NITD-304

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